Surgical castration by orchidectomy

Surgical castration is the simplest and cheapest way to treat metastatic prostate cancer. The obvious disadvantage is the psychological effect of the loss of the testicles.

LHRH-analogues

LHRH-analogues and oestrogen achieve a "medical castration" by stopping the testicular production of testosterone. LHRH-analogues are injections that have to be given monthly or three monthly for the rest of the patient's life. They are effective but very expensive.